Dr Adam Simon, general practitioner and director of Private GP Extra, has delivered high-quality healthcare for more than three decades. Private GP Extra provides flexible, extended appointment times across six locations in Greater Manchester and Cheshire, including evening clinics. The service offers support for weight loss management, along with general health concerns, women’s health, men’s health, lipid issues and bespoke health screening.

How do weight loss injections work?

Weight loss injections, like Ozempic, Wegovy, and Mounjaro, use hormones (GLP-1 and GIP) to reduce appetite and influence metabolism. They slow stomach emptying, making you feel fuller for longer, which signals the brain to reduce hunger and cravings. While it’s possible to lose weight without these injections, the medications make GLP-1 work more effectively than food alone, helping many people manage their appetites and stick to weight loss goals. 

What are the side effects and how safe are these injections?

Most people experience mild side effects such as nausea, changes in bowel habits, or burping. Rare, but more serious effects include pancreatitis (0.2–0.4%), gallbladder problems (0.6%), heart rate or mood changes, and extremely rarely, thyroid cancer (0.00001%). It’s important to use these medications under a doctor’s supervision to ensure they are safe, especially if you have pre-existing conditions or take other medications. 

How do I get the most from the injections? 

It’s important to have a doctor assess if these injections are suitable for you and provide guidance on dosage, monitoring, and side-effect management. Stopping the injections should also be planned with a doctor, often gradually, to maintain appetite control and prevent weight regain. Support plans can help patients safely reduce medication and sustain their weight loss over time.